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tobacco alkaloids

" in MedChemExpress (MCE) Product Catalog:

By Targets:	TMV (1) Amyloid-β (2) Cytochrome P450 (1) Endogenous Metabolite (4) nAChR (5) NF-κB (1)
By Research Areas:	Cancer (1) Infection (1) Inflammation/Immunology (4) Metabolic Disease (2) Neurological Disease (5)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: TMV

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W015806

3-Pyridineacetic acid

Endogenous Metabolite Others

3-Pyridineacetic acid is a higher homologue of nicotinic acid, a breakdown product of nicotine (and other tobacco alkaloids) .

3-Pyridineacetic acid	Endogenous Metabolite	Others
3-Pyridineacetic acid is a higher homologue of nicotinic acid, a breakdown product of nicotine (and other tobacco alkaloids) .

HY-W004515

3-Pyridylacetic acid hydrochloride	Endogenous Metabolite	Others
3-Pyridineacetic acid hydrochloride is a higher homologue of nicotinic acid, a breakdown product of nicotine (and other tobacco alkaloids) .

HY-W001909

Myosmine	nAChR	Metabolic Disease
Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a K_i of 3300 nM .

HY-B1178

Cotinine 1 Publications Verification (-)-Cotinine; (S)-Cotinine; NIH-10498	Endogenous Metabolite	Cancer
Cotinine ((-)-Cotinine), an alkaloid in tobacco and a major metabolite of nicotine, is used as a biological indicator to measure the composition of tobacco smoke

HY-126047A

(R,S)-Anatabine 1 Publications Verification	Others	Inflammation/Immunology
(R,S)-Anatabine is a a minor tobacco alkaloid found in the Solanaceae family of plants that can be used as a specific marker for the detection of tobacco use .

HY-126047AR

(R,S)-Anatabine (Standard)	Others	Inflammation/Immunology
(R,S)-Anatabine (Standard) is the analytical standard of (R,S)-Anatabine. This product is intended for research and analytical applications. (R,S)-Anatabine is a a minor tobacco alkaloid found in the Solanaceae family of plants that can be used as a specific marker for the detection of tobacco use .

HY-W004515S

3-Pyridylacetic acid-d4 hydrochloride	Endogenous Metabolite	Others
3-Pyridylacetic acid-d₄ (hydrochloride) is the deuterium labeled 3-Pyridylacetic acid hydrochloride[1]. 3-Pyridineacetic acid hydrochloride is a higher homologue of nicotinic acid, a breakdown product of nicotine (and other tobacco alkaloids)[2][3].

HY-126047

(S)-(-)-Anatabine	Others	Others
(S)-(-)-Anatabine is a Ti plasmid mutant. (S)-(-)-Anatabine has the activity of inducing tobacco blastoma to transform into nicotinic alkaloids. (S)-(-)-Anatabine can be used in the study of biotransformation of cotyl teratoma .

HY-W001909S

Myosmine-d4	nAChR	Metabolic Disease
Myosmine-d₄ is the deuterium labeled Myosmine. Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a Ki of 3300 nM[1][2].

HY-B1532

Anabasine (S)-Anabasine; (+)-Anabasine	nAChR	Neurological Disease
Anabasine ((S)-Anabasine) is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC₅₀=0.7 µM) .

HY-W014928

Anabasine hydrochloride (S)-Anabasine hydrochloride; (+)-Anabasine hydrochloride	nAChR	Neurological Disease
Anabasine ((S)-Anabasine) hydrochloride is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC₅₀=0.7 µM) .

HY-N12249

7-Deoxy-trans-dihydronarciclasine	Amyloid-β TMV	Infection Neurological Disease Inflammation/Immunology
7-Deoxy-trans-dihydronarciclasine, an alkaloid, is a tobacco mosaic virus (TMV) inhibitor (IC₅₀: 1.80 μM). 7-Deoxy-trans-dihydronarciclasine is an anti-neuroinflammatory agent. 7-Deoxy-trans-dihydronarciclasine decreases the Aβ and APP levels in the cerebral cortex of Tg2576 mice .

HY-135560

Nicotelline Nicotellin	Cytochrome P450	Neurological Disease
Nicotelline (Nicotellin) is a nicotine-related alkaloid, as well as a weak inhibitor of human cDNA-expressed cytochrome P-450 2A6 (CYP2A6). CYP2A6 mediates coumarin 7-hydroxylation, while Nicotelline fails to exhibit inhibition at 300 μM. Nicotelline can be used as a tracer and biomarker of particulate matter (PM) derived from tobacco smoke .

HY-19918A

Anatabine dicitrate	NF-κB Amyloid-β nAChR	Neurological Disease Inflammation/Immunology
Anatabine dicitrate is a tobacco alkaloid that can cross the blood-brain barrier. Anatabine dicitrate is a potent α4β2 nAChR agonist. Anatabine dicitrate inhibits NF-κB activation lower amyloid-β (Aβ) production by preventing the β-cleavage of amyloid precursor protein (APP). Anatabine dicitrate has anti-inflammatory effects and has the potential for neurodegenerative disorders treatment .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W015806

3-Pyridineacetic acid	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
3-Pyridineacetic acid is a higher homologue of nicotinic acid, a breakdown product of nicotine (and other tobacco alkaloids) .

HY-W004515

3-Pyridylacetic acid hydrochloride	Structural Classification Alkaloids Classification of Application Fields Source classification Other Diseases Pyridine Alkaloids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
3-Pyridineacetic acid hydrochloride is a higher homologue of nicotinic acid, a breakdown product of nicotine (and other tobacco alkaloids) .

HY-W001909

Myosmine	Alkaloids Pyrrole Alkaloids Classification of Application Fields Nicotiana tabacum L. Source classification Pyridine Alkaloids Metabolic Disease Plants Solanaceae Disease Research Fields	nAChR
Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a K_i of 3300 nM .

HY-B1178

Cotinine 1 Publications Verification (-)-Cotinine; (S)-Cotinine; NIH-10498	Alkaloids Structural Classification Pyrrole Alkaloids Nicotiana tabacum L. Classification of Application Fields Source classification Other Diseases Pyridine Alkaloids Solanaceae Plants Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Cotinine ((-)-Cotinine), an alkaloid in tobacco and a major metabolite of nicotine, is used as a biological indicator to measure the composition of tobacco smoke

HY-B1532

Anabasine (S)-Anabasine; (+)-Anabasine	Alkaloids Piperidine Alkaloids Structural Classification Nicotiana tabacum L. Source classification Pyridine Alkaloids Solanaceae Plants	nAChR
Anabasine ((S)-Anabasine) is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC₅₀=0.7 µM) .

HY-N12249

7-Deoxy-trans-dihydronarciclasine	Hosta plantaginea (Lam.) Aschers. Structural Classification Alkaloids Source classification Quinoline Alkaloids Plants Asparagaceae Juss.	Amyloid-β TMV
7-Deoxy-trans-dihydronarciclasine, an alkaloid, is a tobacco mosaic virus (TMV) inhibitor (IC₅₀: 1.80 μM). 7-Deoxy-trans-dihydronarciclasine is an anti-neuroinflammatory agent. 7-Deoxy-trans-dihydronarciclasine decreases the Aβ and APP levels in the cerebral cortex of Tg2576 mice .

Cat. No.	Product Name	Chemical Structure

HY-W001909S

Myosmine-d4
Myosmine-d₄ is the deuterium labeled Myosmine. Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a Ki of 3300 nM[1][2].

HY-W004515S

3-Pyridylacetic acid-d4 hydrochloride
3-Pyridylacetic acid-d₄ (hydrochloride) is the deuterium labeled 3-Pyridylacetic acid hydrochloride[1]. 3-Pyridineacetic acid hydrochloride is a higher homologue of nicotinic acid, a breakdown product of nicotine (and other tobacco alkaloids)[2][3].

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tobacco alkaloids

Inhibitors & Agonists

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Isotope-Labeled Compounds

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